to be held as part of IEEE/ACM CCGrid 2014
Chicago, USA, May 26-29, 2014


In the last 20 years, computational methods have become an important part of developing emerging technologies for the field of bioinformatics and biomedicine. Research areas such as biomodelling, molecular dynamics, genomics, neuroscience, cancer models, evolutionary biology, medical biology, biochemistry, biophysics, biotechnology, cell biology, nanobiotechnology, biological engineering, pharmacology, genetics therapy, or automatic diagnosis, rely heavily on large scale computational resources as they need to manage Tbytes or Pbytes of data with large-scale structural and functional relationships, TFlops or PFlops of computing power for simulating highly complex models, or many-task processes and workflows for processing and analyzing data.

As applications require more and more computational resources every day in order to increase the knowledge of biological and health processes, bio disciplines create new challenges of scale for computation, storage, and interpretation of petascale data that are difficult to solve with single clusters. Cloud computing has the potential to help solve these problems by offering a utility model based on highly flexible computing and storage capabilities and abstraction layers that allows overcoming many of the constraints present in dedicated systems. It may also increase research productivity by allowing sharing applications, tools, and algorithms in an easy way.

The aim of the workshop is to promote the synergies of the cloud computing and bio communities by exploring applications developed in clouds, cloud systems enhancements for bio, and new trends and needs shared between both communities.Thus, this workshop will feature articles that discuss the application of cloud computing to bioinformatics and biomedicine, including solutions to area problems and architectural adaptation of cloud systems to fit those problems.


Areas of interest of the workshop include, but are not limited to:
  • Cloud-based bioinformatics applications
  • Cloud-based biomedicine applications
  • Cloud-based application in public health systems
  • Modeling and simulation of complex biological processes
  • Genomics and Molecular Structure evolution
  • Molecular Dynamics
  • Data intensive biomedical applications
  • Clouds for big data manipulation in bioinformatics and biomedicine
  • Ontologies and biomedical text mining using clouds
  • Biological data mining and visualization using clouds
  • Managing large scale biological and biomedical databases using clouds
  • Visualization and analysis of biomedical images
  • Integration and analysis of biomedical data
  • Biosignals processing using clouds
  • Computational Modeling and Data Integration
  • Privacy issues for cloud-based biomedical applications
  • Security challenges in big data and biomedicine
  • Biocloud services and resource specification
  • Cloud Computing architectures for bio
  • Data-centric versus computer-centric cloud architectures
  • Hybrid infrastructures (cloud/physics) for bio applications
  • Resource provisioning for bioclouds
  • Distributed cloud solutions
  • Cloud solutions for biosensors and mobility
  • Improved energy consumption of bio applications using clouds
  • Programming paradigms and tools for bio-applications
  • Important dates

  • Submission: February 16th, 2014 - Deadline extended
  • Author notification: March 1st, 2014
  • Camera Ready papers due: March 14th, 2014
  • Conference: May 26th-29th, 2014
  • Committee

    Workshop Organizers:
  • Prof. Jesus Carretero. University Carlos III of Madrid, Spain
  • Dr. Javier Garcia Blas. University Carlos III of Madrid, Spain
  • Dr. Manuel Desco. Hospital Gregorio Marañon de Madri, Spain
  • Prof. Dana Petcu. University of Timisoara, Romania

  • Program Committee:
  • Ivona Brandic. Vienna University of Technology, Austria
  • Rajkumar Buyya, The University of Melbourne, Australia
  • Alejandro Calderon. University Carlos III of Madrid, Spain.
  • David E. Singh. University Carlos III of Madrid, Spain.
  • Geoffrey Fox. Indiana University, USA
  • Jose Daniel Garcia. University Carlos III of Madrid, Spain.
  • Felix Garcia-Carballeira. University Carlos III of Madrid, Spain.
  • Wolfgang Gentzsch. The UberCloud, USA
  • Pesole Graziano. University of Bari, Italy
  • Hsien-Da Huang. National Chiao Tung University, HsinChu, Taiwan
  • Florin Isaila, Argonne National Labs, USA
  • Cedrid Notredame. Center For Genomic Simulation, Spain
  • Javier Pascau, University Carlos III of Madrid, Spain
  • Xinyu Que, IBM T.J. Watson Researcher Center, USA
  • Jorge Ripoll, University Carlos III of Madrid, Spain
  • Ivan Rodero, Rutgers University, USA
  • Omer F. Rana. Cardiff University, UK
  • Saman K. Halgamuge. The University of Melbourne, Australia
  • Domenico Talia. University of Calabria, Italy
  • Peter J. Tonellato. Center for Biomedical Informatics, Harvard Medical School, USA
  • Oswaldo Trelles.University of Malaga. Spain
  • Jose Luis Vazquez-Poletti, University Complutense of Madrid, Spain
  • Miguel A. Vega-Rodriguez. University of Extremadura, Spain
  • Tin Wee Tan. National University of Singapore. Singapore
  • Roel Wuyts, IMEC, Belgium
  • Laurence T. Yang. St. Francis Xavier University, Canada
  • Paper submission guidelines

    Authors are invited to submit papers electronically in PDF format. Submitted manuscripts should be structured as technical papers and may not exceed 10 letter-size (8.5 x 11) pages including figures, tables and references using the IEEE format for conference proceedings. Submissions not conforming to these guidelines may be returned without review. Authors should make sure that their file will print on a printer that uses letter-size (8.5 x 11) paper. The official language of the conference is English. All manuscripts will be reviewed and will be judged on correctness, originality, technical strength, significance, quality of presentation, and interest and relevance to the conference attendees.

    Paper submissions are limited to 10 pages in 2-column IEEE format including all figures and references. Submitted manuscripts exceeding this limit will be returned without review. For the final camera-ready version, authors with accepted papers may purchase additional pages at the following rates: 100 USD for each of the first two additional pages; 200 USD for each of the third and fourth additional pages.

    The paper submission online system is open:

    Special issue

    Extended versions of distinguished selected papers accepted and presented in C4Bio 2014, after further revisions, will be published in a special issues of the Scalable Computing: Practice and Experience journal (SCPE) that is indexed in SCOPUS.


    Program May 26, 8:30h-17:30h at Hyatt Regency Chicago, 151 East Wacker Drive

    The workhop is jointly held as a full-day event together with Workshop on Clusters, Clouds and Grids for Health CCGrid Health. The workshop fees are included into the CCGrid 2014 conference fees. One day registration is possible via the main conference registration.

    Introduction and Keynotes
      8:45 -   9:00 Welcome and Introduction
      9:00 - 10:00 Keynote CCGrid-Health: Robert Grossman
    Biomedical Clouds and Biomedical Data Commons And Why They Are Changing Health Care Research
    10:00 - 10:30 Keynote C4Bio: Jesus Carretero
    Sustainable Ultrascale Computing Systems: Applications in Biomedicine and Bioengineering
    Coffee Break
    CCGrid-Health Session
    11:00 - 12:30 Global Initiative for Sentinel e-Health Network on Grid (GINSENG), Medical data integration and semantic developments for epidemiology
    Sébastien Cipière, Guillaume Ereteo, Alban Gaignard, Nouha Boujelben, Sébastien Gaspard, Vincent Breton, Frédéric Cervenansky, David Hill, Tristan Glatard, David Manset, Johan Montagnat, Jérôme Revillard and Lydia Maie.
    Extending XNAT towards a Cloud-based Quality Assessment Platform for Retinal Optical Coherence Tomographies
    Jie Wu, Christoph Jansen, Maximilian Beier, Michael Witt and Dagmar Krefting
    Distributed Detection of Cancer Cells in Cellular Spike Streams
    Abdul Hafeez, M. Mustafa Rafique and Ali R. Butt
    Lunch Break
    C4Bio Session 1
    13:30 - 15:00 Accelerating Comparative Genomics Workflows in a Distributed Environment with Optimized Data Partitioning
    Olivia Choudhury, Nicholas Hazekamp, Douglas Thain and Scott Emrich
    Integration of Clustering and Multidimensional Scaling to Determine Phylogenetic Trees as Spherical Phylograms Visualized in 3 Dimensions Yang Ruan, Geoffrey L. House, Saliya Ekanayake, Ursel Schütte, James D. Bever, Haixu Tang and Geoffrey C. Fo
    A Survey of Approches and Frameworks to Carry out Genomic Data Analysis on the Cloud Philip Church and Andrzej Goscinski
    A storage policy for a hybrid federated cloud platform executing bioinformatics applications Deric Lima, Breno Moura, Gabriel Oliveira, Edward Ribeiro, Aleteia Araujo, Maristela Holanda, Roberto Togawa and Maria Emilia Walter
    Coffee Break
    C4Bio Session 2
    15:30 - 16:30 A Performance Evaluation of Sequence Alignment Software in Virtualized Environments Zachary J. Estrada, Zachary Stephens, Cuong Pham, Zbigniew Kalbarczyk and Ravishankar K. Iyer
    From scripted HPC-based NGS pipelines to workflows on the cloud Jacek Cala, Yaobo Xu, Eldarina Azfar Wijaya and Paolo Missier
    Evaluation of the feasibility of making large-scale X-ray tomography reconstructions on clouds Estefania Serrano, Guzman Bermejo, Javier Garcia Blas and Jesus Carretero
    16:30 - 17:30 Conclusion and Closing

    Organized by